valve regulated lead acid battery Effects of lead exposure on the status of platelet indices in workers involved in a lead-acid battery manufacturing plant

This study aims to determine the effect of lead exposure on platelet index status of lead exposed workers
Acid battery factory process.
The platelet index and blood lead level (BLLs) were measured in 429 male workers.
BLLs were determined by atomic absorption spectrometer.
Platelet index in samples quantified with Sysmex KX-
21 blood analyzer.
The levels of platelet count (alt), platelet count (PCT) and mean platelet mass (MPM) decreased significantly, the width of platelet distribution (PDW), the ratio of platelet to large cells (P-
The mean platelet volume increased with the increase of BLLs.
The results of linear multiple regression analysis showed that platelet count (β _ 0. 143, P=0. 005), PCT (β-0. 115, P=0.
023) and MPM (β-0. 110, P=0.
030) with BLLs and P-LCR (β 0. 122, P=0.
016) positive correlation with BLLs.
The body mass index variable was positively correlated with PCT (β 0. 105, P=0.
032) and MPM (beta 0. 101, P=0. 039).
The results of this study may indicate that lead exposure may reduce the damage to coagulation function through endothelial tissue damage and no.
This study is a cross
Segmented study conducted in 429 male subjects
Located in the acid battery manufacturing plant in Tamil Nadu, India.
Platelet index in lead
The exposure workers were compared with age, body mass index (BMI), experience, drinking, smoking, lead level (BLL) and Work category.
Prior to incorporating them into the study, each of them received informed consent.
Collect demographic data, career history and habits of subjects (smoking and drinking) by prior use)
Design Questionnaire.
BMI was calculated by subjective weight (kg) and height (m) and expressed by kg/m.
3 ml venous whole blood was collected from the worker with a heparin vacuum cleaner and stored at 20 °c until the analysis was performed.
2 ml of blood is digested by using a spirit
D milestone microwave system with 2 ml of nitric acid (HNO) and 0 (Italy ).
2 ml of hydrogen peroxide (HO) by holding power, temperature and duration.
The digested sample uses triple-
Distilled water, centrifugal.
Determination of lead concentration in blood Atomic Absorption Spectrometer (GBC-
Avanta, Australia ).
Preparation of 20g/dl of standard solution from Merck's lead standard solution (1. 19776.
0500) and added to the minimum concentration of the sample, the analysis found that the recovery rate was 100% at